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guide1 - BME 201, Spring 2011 - Test#1 Study Guide Model of...

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BME 201, Spring 2011 - Test#1 Study Guide Model of Passive Membrane 1. Draw an RC circuit model of a passive membrane. Explain the physical meaning of all circuit components. Explain the difference in the meaning of potentials in the models of active membrane and passive membrane. 2. Write a governing differential equation for passive membrane, find the solution for stimulation with a step current. 3. Given a small cell stimulated by an intracellular microelectrode, find its RC circuit analog and determine the parameters of this circuit. 4. Explain why the model of passive membrane can be used to estimate the threshold for excitation. What is the condition for excitation? 5. Derive the strength-duration relationship, draw the strength-duration curve, indicate rheobase and chronaxie. 6. What is the importance of chronaxie? 7. What is the difference between a strength-duration curve and a strength-interval curve? Introduction to Membrane Biophysics 1. What are the fluxes of ions due to (a) concentration gradient, (b) potential gradient? What are the corresponding current densities? 2. Explain the meaning of electrochemical gradient. 3. Given the Nernst-Planck equation, describe the physical meaning of its two terms.
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This note was uploaded on 09/03/2011 for the course BME 233 taught by Professor Izatt during the Spring '11 term at Duke.

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guide1 - BME 201, Spring 2011 - Test#1 Study Guide Model of...

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