Gene Regulation and Mutation

Gene Regulation and Mutation - Gene Regulation of...

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Describe how gene structure enables protein/gene regulation in prokaryotes and Eukaryotes. Describe different types of mutations and predict their effect on the entire genome. Prokaryotes Operon – the entire system of DNA (that’s responsible for making a protein (starting transcription). Only in prokaryotes. Most common one - lac operon. RNA Polymerase binds to operator and promoter and starts transcribing. Repressor protein: a stopping protein attached to the operator. Therefore, the repressor has to be removed to turn on the gene/start transcribing. When lactose comes and binds to the repressor protein, it’s no longer bound to the operator, and leaves, so the gene is turned on again. Lactase (enzyme) helps get rid of the lactose which is bound to the repressor. When the lactose moves out, the repressor protein changes shape and doesn’t bind to the operator anymore. Lactase turns the lactose into ATP or sugar, and it leaves the repressor. | P a g e
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This note was uploaded on 09/06/2011 for the course BIO 201 taught by Professor Mr.bajom during the Spring '09 term at Abu Dhabi University.

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Gene Regulation and Mutation - Gene Regulation of...

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