Defenses Against Infection

Defenses Against Infection - Defenses Against Infection...

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Unformatted text preview: Defenses Against Infection Innate and Adaptive Figure 81 Human Pathogens Figure 82 part 1 of 4 Figure 82 part 2 of 4 Figure 82 part 4 of 4 Pathogenic Mechanisms Exotoxins, endotoxins, cytopathic effect, immune complexes, antihost antibody and cellmediated immunity Figure 83 part 1 of 2 Figure 83 part 2 of 2 Figure 84 Innate and Acquired Immune Responses Figure 85 Figure 86 part 1 of 2 Figure 86 part 2 of 2 Figure 87 Complement Activation by the Alternate Pathway This can occur in the fluid phase or on the bacterial cell surface Figure 88 Figure 89 Importance of Control Proteins in the Alternate pathway Properdin, DAF, and MCP Figure 810 part 1 of 2 Figure 810 part 2 of 2 Other plasma proteins are involved in the control of infection Serpins, 2 Macroglobulin Figure 811 part 1 of 2 Figure 811 part 2 of 2 Cellular Mechanisms of the Immate Immune System Phagocytosis, cytokine production Phagocytosis, cytokine production and natural killer cell activity Figure 812 Figure 813 Figure 814 Figure 815 Chemokines Chemoattractant cytokines Two major subgroups CC and CXC. Based on pairs of cysteine residues which are adjacent (CC) or separated by another amino acid (CXC). Figure 816 part 1 of 3 Figure 816 part 2 of 3 Sometimes Cytokines Can Cause Pathologic Reactions Figure 818 part 1 of 3 Figure 818 part 2 of 3 Figure 818 part 3 of 3 Neutrophils Figure 819 Figure 820 Killing By Macrophages and Neutrophils Figure 821 Inflammatory Cytokines These molecules have multiple effects, including raising the body core temperature, recruiting dendritic cells and stimulation of acute phase proteins. Figure 822 Acute Phase Proteins Figure 823 Interferons Virally infected cells are stimulated to produce type I interferons. Figure 825 Figure 826 Figure 828 Natural Killer cells NK cells express both inhibitory and activating receptors Figure 829 Figure 832 Figure 833 part 2 of 2 The Role of Unusual T and Bcells in innate immunity B1 cells and Tcells Figure 834 Figure 835 Figure 836 Conventional Adaptive Immunity Figure 845 Figure 846 Figure 847 Figure 852 Summary Figure 853 ...
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