Chapter 72 Sexual Dysfunction.docx - CHAPTER 72 SEXUAL DYSFUNCTION \u25cf Drugs that can lead to ED\/Sexual Dysfunction \u25cb Antidepressants especially SSRIs

Chapter 72 Sexual Dysfunction.docx - CHAPTER 72 SEXUAL...

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CHAPTER 72 SEXUAL DYSFUNCTION Drugs that can lead to ED/Sexual Dysfunction: Antidepressants especially SSRIs and SNRIs (dec libido) AntiHTNs such as BB, clonidine, and others APs: first generation, prolactin raising second gen BPH meds such as finasteride, dutasteride, and silodosin Natural products: Yohimbe L-arginine Panax ginseng PDE-5 INHIBITORS: cause a local release of NO which inc cGMP and causes smooth muscle relaxation which inc blood flow to penis CI: do not use with nitrates or riociguat May cause impaired color discrimination (dose related,) hearing loss, vision loss, hypotension, priapism, and CVD SE: HA, flushing, dizziness, dyspepsia No more than one dose/day is needed Stendra can be taken closest to sexual activity Reduce dose if: > 65 YO Using an alpha blocker Using a 3A4 inhibitor Severe renal/liver disease Sildenafil: (Viagra) 25-100 mg daily Start at 50 mg; take 1 hour before sexual activity Revatio is used for PAH Vardenafil: (Levitra or Staxyn ODT) 5-20 mg daily or
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  • Spring '17
  • vision loss, PAH, ALPHA BLOCKER, Clonidine, 5HT1

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