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HMB265 Final 2003 014 - I—_—-——-— 59 How does the...

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Unformatted text preview: I—_____.___—-——-— 59. How does the cytoskeleton contribute to the establishment of the Drosophila anterior— posterior axis? 3) Through microtubule-directed tethering 0f localized transcriptiOn factors b) Through microtubule control of the orientation of mitotic cleavages c) Through microfilarnent—directed asymmetric cell divisions d) Through microfilament control of the orientation of mitotic cleavages e) None of the above 60. In Drosophila, the nos gene contributes to anterior-posterior patterning by inhibiting translation of HB-M in the posterior portion of the oocyte. What would happen if the 3' untranslated region (3' UTR) of the HB-M mRNA were replaced with the 3' UTR of a gene not sensitive to translation regulation? a) There would be a loss of anterior segments. ’0) There would be no change in the segmentation pattern of the embryo because the BCD gradient would remain unchanged. c) The HB-M protein gradient would be reversed. d) Normal dorsal-ventral pattern formation would be disrupted. e) HB—M protein would be produced at high levels everywhere in the embryo. 61. In a human population, the genotype frequencies at one locus are 0.5 AA, 0.4 An, and 0.1 no. The frequency of theA allele is a) 0.20 h} 0.32 c) 0.50 d) 0.70 e) 0.90 62. Suppose that you are a genetic counselor, and a couple seeks your advice about BHT tasting (people who can taste BHT in processed food are recessive homozygotes for the "taster" allele and non—tasters are homozygous dominant or heterozygous for the "noun taster" allele). Both prospective parents are non—tasters, but a careful analysis of the husband's pedigree reveals that he is a carrier of the taster allele. The two alleles are in Hardy—Weinberg equilibrium, and the proportion of Eli-[T tasters in the population is 16 percent. What is the probability that the couple's first child will be a nan—taster of BHT? a) 0.0 b) 0.32 c) 0.81 d) 0.86 e) 1.0 Paget5of‘18 ...
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