5.2 - o Imprinting is when one of a pair of gens on...

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DNA methylation is related to diseases and histone modification o Hypo and hyper methylation are observed in some disease states such as immune deficiencies and cancer o Methlated CpG islands are bound by specific binding proteins called MeCPs o These are components of proteins complexes including HDACs Methylation is related to genomic imprinting and X-inactivation
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Unformatted text preview: o Imprinting is when one of a pair of gens on homologous chromosomes is silenced by DNA methylation o It is termed imprinting b/c the methylation state is transmitted from one generation to the next Imprint control elements are the where is takes place...
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This note was uploaded on 09/07/2011 for the course BIO 01:119:101 taught by Professor Marin during the Spring '08 term at Rutgers.

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