11.4 MG - by causing the repressor to not bind Single...

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o Heat shock not recognized by normal RNAP. Different promoter Change one of subunits RNPA changes what it interacts with
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This is an example of inducible negative control. The lac promoter is intrinsically fit. The role of the repressor is to block RNAP from initiating induction is achieved by causing the repressor to not bind. (inducible negative control) An example of repressible negative control. The Trp promoter is intrinsically fit. The role of the repressor is to block RNAP from initiating. Induction is achieved
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Unformatted text preview: by causing the repressor to not bind. Single protein controls genes throughout the genome (trp repressor) Positive control o Promoter is intrinsically weak, meaning RNAP does not bind Well o RNAP needs help binding to promoter o Accessory proteins Help RNAP bind o Example Catabolite activation o Catabolite Activator protein binds DNA and also binds RNAP...
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11.4 MG - by causing the repressor to not bind Single...

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