11.5 MG - Coavtivators o Prteins that active via non-specific DNA binding or thru protein-protein interactions o Histone acetylation complexes(SAGA

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Cell-specific modules o Subcategory of a modulator- responsible for regulation under a specific condition. Response modules- o Heat shock (HSTF) Developmental o Antennapedia- freak fly An added level of complexity- alternative promoters (each w/ basal and response elements) Activators enhance promoter activity They can regulate one gene or many genes (at enhancer element) They can function alone or in conjunction with co-activators.
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Unformatted text preview: Coavtivators o Prteins that active via non-specific DNA binding or thru protein-protein interactions o Histone acetylation complexes (SAGA) o Bridging protein (enhanceosome) (SRY) distorts DNA bringing together non-adjacent sites. Repressors o Histone deacetlyation complexes o DNA methylation complexes o Proteins that bind to basal elements ex TATA element....
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This note was uploaded on 09/07/2011 for the course BIO 01:119:101 taught by Professor Marin during the Spring '08 term at Rutgers.

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11.5 MG - Coavtivators o Prteins that active via non-specific DNA binding or thru protein-protein interactions o Histone acetylation complexes(SAGA

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