10.4 - o Different domains exist some resistant to DNASe1...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Accessing the genome How are genomes replicated, gene expression what happens to it???? DNA content of nucleolus. o Spaghetti model vs Tokyo subway model Chromatin Domains o Heterochromatin- compact organization electron dense o Constitutive heterochromatin- permanent feature o Facultative moves in and out of heterochromtic state o Euchromatin loosely organized less election dense Functional domain 40-100 bp in length
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: o Different domains exist some resistant to DNASe1 Dnase1 hypersensitivity used to define functional domains. Insulators first identified in drophila SCS- specialized chromatin structures o Segment of DNA that acts as the boundary pt b/t 2 functional domains o Insulators block the regulatory signals that control gene expression. Regulatory signals influence gene expression...
View Full Document

This note was uploaded on 09/08/2011 for the course BIO 01:119:101 taught by Professor Marin during the Spring '08 term at Rutgers.

Ask a homework question - tutors are online