10.4 - o Different domains exist some resistant to DNASe1...

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Accessing the genome How are genomes replicated, gene expression what happens to it???? DNA content of nucleolus. o Spaghetti model vs Tokyo subway model Chromatin Domains o Heterochromatin- compact organization electron dense o Constitutive heterochromatin- permanent feature o Facultative moves in and out of heterochromtic state o Euchromatin loosely organized less election dense Functional domain 40-100 bp in length
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Unformatted text preview: o Different domains exist some resistant to DNASe1 Dnase1 hypersensitivity used to define functional domains. Insulators first identified in drophila SCS- specialized chromatin structures o Segment of DNA that acts as the boundary pt b/t 2 functional domains o Insulators block the regulatory signals that control gene expression. Regulatory signals influence gene expression...
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