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10.5 - • How do you characterize bacteria o 16s rRNA •...

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Most prokaryote genomes are less than 5 mb but range in zize form .5-30 MV The size of most genomes is proportional to the number of genes average 950 genes per 1 mb Largest genomes are in free-living prokatyoes and the smallest are in obligate parasites. Prokaryotic genomes pose a problem for the species concept o o K12 genome 4.64 Mb, 528 k genes (12%) o Bad News microbe o Can these two be the sames species??? By comparison human and mouse have 99% of the genome.
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Unformatted text preview: • How do you characterize bacteria? o 16s rRNA • Lateral (horizontal) gene transfer o Genes acquired from other species, vs. vertical gene transfer (descent) Transformation • Metagenomics reveals that most prokaryotes remain unidentified o Only prokaryotes that can be cultured have been studied and genomes sequenced o Until now metagenomics o Obtain and sequence DNA from and environment, seawater, soil, hot springs...
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