Unformatted text preview: • 4 extracellular segments, 4 cytosolic regions • B-adrenergic for epinephrine • Alpha subunit transduces the signal to effector ( alpha s stimulates , alpha i inhibits ) • FRET: detects G protein activation bc YFP on gamma is activated only when its near the tag on alpha. • C3 loop is where G Proteins bind- determined by chimeric receptors • Response specificity is determined by type of ligand, GPCR, G protein, & effector • Beta gamma subunit associates with K+ channels = open, heart muscle regulation...
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This note was uploaded on 09/08/2011 for the course CELL BIO & 01:146:473 taught by Professor Brewer during the Spring '11 term at Rutgers.
- Spring '11