Chapter 14 DNA SYNTHESIS

Chapter 14 DNA SYNTHESIS - Chapter14DNASYNTHESIS The start...

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Chapter 14  DNA SYNTHESIS The start of a scientific revolution History Meichner discovered DNA in 1869 – 4 years after Mendel published his work. Levene analyzed DNA and found 3 components (collectively called a nucleotide). 1. 2. 3. Watson and Crick: Double helix ALWAYS! - adenine pairs with thymine and cytosine with guanine. DNA has specific ends: 3’ = OH group, 5’ = PO 4 group and the 2 stands are antiparallel. Figure 14-6 DNA Structure - Review 2 strands wound into a double helix. Strands are held together by hydrogen bonds between “complementary bases ”. Watson and Crick proposed that each strand could be used as a template to make new strands of DNA because they are “complementary”. Requires that the 2 strands be unwound or unzipped. Example: Original DNA: 5’ – CAGT – 3’ 3’ – GTCA – 5’ To copy: Original strand 1: 5’ – CAGT – 3’ 1
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New strand 1: 3’ – GTCA – 5’ Original strand 2: 3’ – GTCA – 5’ New strand 2: 5’ – CAGT – 3’
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This note was uploaded on 09/08/2011 for the course BIOL 1403 taught by Professor Dini during the Fall '09 term at Texas Tech.

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Chapter 14 DNA SYNTHESIS - Chapter14DNASYNTHESIS The start...

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