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Lecture 01 - Lecture 1 Introductory Concepts Monday August...

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Lecture 1: Introductory Concepts Monday, August 24 th Reading assignment: Chapter 1 Overview - De nition of life systems - General description of biochemistry - Chemical functional groups - Introduction to biomolecules four classes of monomer and polymers - Chemical reactions in life systems six classes - De nition of metabolism
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Characteristics of “Life Systems” Founded on chemical principles Self-sustaining Controlled catalysis Molecules organized in separable physical units - cells Informational molecules Adaptation of the system Capture energy from environment
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Objectives of the Field of Biochemistry Isolate and chemically de ne biomolecules - reductionist approach Identify speci c chemical reactions Chemical mechanisms - catalysis - information processing and adaptation - energy capture, storage, utilization - regulation, signal transmission and response Integrate many speci c details into single comprehensive system
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Relationships Between Di ff erent Life Systems Species are distinct chemical systems Adaptation is evolution - systems adapt until they become distinct Similar characteristics reveal relationships
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