Lecture 03, 04; Water

Lecture 03, 04; Water - Lectures 3 and 4: Water in...

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Unformatted text preview: Lectures 3 and 4: Water in Biological Systems Friday, August 28 th ; Monday, August 31 st Reading assignment: Chapter 3 Overview- Polar molecules and solvent effects- Weak bonds and hydrophobic effect- pH scale and weak acids- Buffers Biological Systems are Water-Based TISSUE % WATER Heart 83 Skeletal muscle 79 Lung 79 Brain 77 Tomato 94 Whole milk 87 Bread 36 Flour 12 Functions of Water in Biological Systems Solvent- dissolves polymers, building block, metabolites Compartmentalization- alkane, alkene molecules not soluble, form barriers- aqueous compartments separated by membranes Stabilize temperature and pH- proton concentration and temperature resistant to change Functions of Water in Biological Systems Chemical reactions- hydrolysis- oxidation-reduction Molecular Structure of Water sp 3 bonding of oxygen, tetrahedral- paired electrons in 2 orbitals- electron shared with H nucleus in 2 orbitals- oxygen is electronegative- assymetric charge distribution polar molecule (dipole) partial positive charge on H ( + ) partial negative charge on O (- ) Hydrogen Bonds assymmetric electron distribution in covalent bonds- partial charges electrostatic interactions between + and - weak compared to covalent bond strongest when three atoms in line extended H bond networks in water occurs with various polar functional groups in addition to water Other Weak Bonds >210 Covalent electrons shared between two nuclei Weak Bonds...
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Lecture 03, 04; Water - Lectures 3 and 4: Water in...

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