19_LectureOutline - Introduction to the Cardiovascular...

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Introduction to the Cardiovascular System 0. A circulating transport system 0. A pump (the heart) 1. A conducting system (blood vessels) 2. A fluid medium ( blood ) 0. Is specialized fluid of connective tissue 1. Contains cells suspended in a fluid matrix 1. To transport materials to and from cells 3. Oxygen and carbon dioxide 4. Nutrients 5. Hormones 6. Immune system components 7. Waste products Functions of Blood 2. Transport of dissolved substances 3. Regulation of pH and ions 4. Restriction of fluid losses at injury sites 5. Defense against toxins and pathogens 6. Stabilization of body temperature Physical Characteristics of Blood 7. Whole Blood 8. Plasma 2. Fluid consisting of: 0. water 1. dissolved plasma proteins 2. other solutes 9. Formed elements 3. All cells and solids 8. Three Types of Formed Elements 10. Red blood cells (RBCs) or erythrocytes 4. Transport oxygen 11. White blood cells (WBCs) or leukocytes 5. Part of the immune system 12. Platelets 6. Cell fragments involved in clotting 13. Hemopoiesis 7. Process of producing formed elements
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8. By myeloid and lymphoid stem cells 14. Fractionation 9. Process of separating whole blood for clinical analysis 0. Into plasma and formed elements 9. Three General Characteristics of Blood 15. 38°C (100.4°F) is normal temperature 16. High viscosity 17. Slightly alkaline pH (7.35–7.45) 10.Blood volume (liters) = 7% of body weight (kilograms) 18. Adult male: 5 to 6 liters 19. Adult female: 4 to 5 liters Plasma 20. Makes up 50–60% of blood volume 21. More than 90% of plasma is water 22. Extracellular fluids 10.Interstitial fluid (IF) and plasma 11.Materials plasma and IF exchange across capillary walls 1. Water 2. Ions 3. Small solutes 11.Differences between Plasma and IF 23. Levels of O 2 and CO 2 24. Concentrations and types of dissolved proteins 12.Plasma proteins do not pass through capillary walls 25. Plasma Proteins 13. Albumins (60%) 4. Transport substances such as fatty acids, thyroid hormones, and steroid hormones 14. Globulins (35%) 5. Antibodies, also called immunoglobulins 6. Transport globulins (small molecules): hormone-binding proteins, metalloproteins, apolipoproteins ( lipoproteins ), and steroid- binding proteins 15. Fibrinogen (4%) 7. Molecules that form clots and produce long, insoluble strands of fibrin 26. Serum 16.Liquid part of a blood sample 8. In which dissolved fibrinogen has converted to solid fibrin 27. Other Plasma Proteins
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17.1% of plasma 9. Changing quantities of specialized plasma proteins 10. Enzymes, hormones, and prohormones 12.Origins of Plasma Proteins 28. 90% + made in liver 29. Antibodies made by plasma cells 30. Peptide hormones made by endocrine organs Red Blood Cells 31. Red blood cells (RBCs) make up 99.9% of blood’s formed elements 32. Hemoglobin 18.The red pigment that gives whole blood its color 19.Binds and transports oxygen and carbon dioxide 33. Abundance of RBCs 20. Red blood cell count : the number of RBCs in 1 microliter of whole blood 11. Male: 4.5–6.3 million
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This note was uploaded on 09/13/2011 for the course BIO 110 taught by Professor Dfiabane during the Spring '11 term at Community College of Philadelphia.

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19_LectureOutline - Introduction to the Cardiovascular...

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