lecture05 fMRI part2

lecture05 fMRI part2 - Lecture 5: Cognitive Neuroscience...

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Unformatted text preview: Lecture 5: Cognitive Neuroscience Methods - fMRI Part 2 Psych 123 Cognitive Neuroscience Methods of Cognitive Neuroscience Patient Studies Neuroimaging Studies Functional Magnetic Resonance Imaging (fMRI) Positron Emission Tomography (PET) Electrophysiological Studies Single-Cell Recordings Event-Related Potential Recordings (ERP) Intra-Cranial Electrode Recordings Transcranial Magnetic Stimulation (TMS) Critical Properties of the BOLD signal Increased BOLD activity can be sustained during the whole course of a neural event. BOLD is directly related to localized cerebral blood flow & oxygen consumption. CBF is greater than OC and it peaks around 6 seconds. This creates a signature hemodynamic response function. BOLD can be sample rapidly (~ 2 secs.) across the whole brain. BOLD can be sampled from a small cube of space (e.g., voxel = 3mm x 3mm x 5mm). Changes in BOLD signal is a challenge to analyze because it is a small signal (< 1% change) in a noisy environment. BOLD is an indirect measure of the summed activity of neural events that are happening across thousands of neurons....
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This note was uploaded on 09/09/2011 for the course PSY 123 taught by Professor Staff during the Spring '11 term at UCSB.

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lecture05 fMRI part2 - Lecture 5: Cognitive Neuroscience...

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