Lecture 04 - Glycolysis Anaerobic breakdown of glucose

Lecture 04 - Glycolysis Anaerobic breakdown of glucose - L...

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Lecture 04 – Glycolysis: Anaerobic breakdown of glucose There’s two pathway to breakdown for energy - Anaerobic (glycolysis) - Aerobic (TCA cycle) - Goal is to capture the chemical energy of Glucose in the form of ATP (taking glucose molecule and capturing energy in the form of ATP) o Nicotinamide Adenine Dinucleotide (NAD/ NADH) NAD is used in catabolic pathway (glycolysis and TCA cycle) NADH has a phosphate and used to drive synthetic pathways (biosynthesis) Capture reducing equivalence can be converted to ATP Standard Free Energy (G) - A constant and is an intrinsic property of any given reaction - One thing you want to consider when you're looking at these processes ( A B) o If B is a lower state than A than you will have negative DeltaG o Know the steps that you need to put in energy! - You want to go through back and forth through the pathways - It determines which pathway needs energy - (Delta)G o ’ = - RTlnK’ eq ; prime = standard conditions for physiological reaction for a cell,
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This note was uploaded on 09/14/2011 for the course PHARM ERM taught by Professor Staff during the Spring '11 term at UCSD.

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Lecture 04 - Glycolysis Anaerobic breakdown of glucose - L...

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