This preview shows page 1. Sign up to view the full content.
Unformatted text preview: Lecture 31 – Placenta Placenta – point is access maternal blood/gas and nutrient exchange Be able to identify location and flow of both maternal and fetal blood through the placenta Early placental development- Villous = placental disc- Extravillous cells that invade into the uterus (so we see the villous trophoblast when we look at the placent)- Blood locations o Fetal blood inside villi o Maternal blood is in the intervillous space- Trophoblast: main epithelial cell type in the placenta- What separates the maternal and fetal blood (3 layers) o Fetal endothelium (three layers of cells-fetal endothelium) extravillous trophoblast (EVT) o Two layers of trophoblasts Cytotrophoblast (CTB) • Stem cells • Proliferative trophoblast Synctiotrophoblast (STB) • Multinucleated • Immediately surrounded by maternal blood o Extravillous trophoblast – carrying fetal blood; invade uterine wall, go toward maternal spinal arterioles (carrying oxygen blood) replace maternal...
View Full Document
This note was uploaded on 09/14/2011 for the course PHARM ERM taught by Professor Staff during the Spring '11 term at UCSD.
- Spring '11