Lecture 31 – Placenta
Placenta – point is access maternal blood/gas and nutrient exchange
Be able to identify location and flow of both maternal and
fetal blood through the placenta
Early placental development
-
Villous
= placental disc
-
Extravillous cells
that invade into the uterus (so we see the
villous trophoblast when we look at the placent)
-
Blood locations
o
Fetal blood inside villi
o
Maternal blood is in the intervillous space
-
Trophoblast: main epithelial cell type in the placenta
-
What separates the maternal and fetal blood (3 layers)
o
Fetal endothelium (three layers of cells-fetal
endothelium)
extravillous trophoblast (EVT)
o
Two layers of trophoblasts
Cytotrophoblast (CTB)
•
Stem cells
•
Proliferative trophoblast
Synctiotrophoblast (STB)
•
Multinucleated
•
Immediately surrounded by maternal blood
o
Extravillous trophoblast – carrying fetal blood; invade
uterine wall, go toward maternal spinal arterioles
(carrying oxygen blood)
replace maternal
This is the end of the preview.
Sign up
to
access the rest of the document.
- Spring '11
- staff
- placenta, Uterus, fetal blood
-
Click to edit the document details