Quiz 01 - Ans

Quiz 01 - Ans - Quiz 1 Answers d. Arise from a common...

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Quiz 1 – Answers Question 1 of 15 Which of the following properties is characteristic of hematopoietic stem cells? a. Efficient phagocytosis b. Multi-lineage differentiation potential c. Independence of the bone marrow niche d. High levels of mRNA coding for hemoglobin alpha and beta chains e. Immortality 1 out of 1 The correct answer is b. Muli-lineage differentiation There are four defining characteristics of hematopoietic stem cells: self-renewal capacity, high proliferative potential, multi-potent differentiation potential, and the ability to home to marrow. They are not themselves involved in phagocytosis, hemoglobin production so a and d incorrect. They are dependent on the surrounding marrow environment so c is incorrect. E is incorrect as even stem cells have a limited longevity. Question 2 of 15 Which of the following does not arise from a common myeloid progenitor? a. Red blood cells b. Platelets c. Eosinophils d. T-cells e. Monocytes 0 out of 1 The correct answer is d. T-cells All non-lymphoid blood cells arise from a common myeloid progenitor Question 3 of 15 Megakaryocytes a. Are stimulated to make platelets primarily by erythropoietin binding to a megakaryocyte transmembrane receptor b. Are smaller than red blood cells c. Create platelets via programmed cell death resulting in platelets budding from the megakaryocyte membrane d. Arise from a common lymphoid progenitor e. Are inhibited by thrombopoietin 0 out of 1 The correct answer is c. Create platelets via programmed cell death resulting in platelets budding from the megakaryocyte membrane a) Megakaryoctyes are primarily stimulated by thrombopoietin, not erhythropoietin b) Megakaryocytes are typically the largest cells in the marrow c) Correct as illustrated by video d) arise from common MYELOID progenitor e) see answer for a) Question 4 of 15 Which of the following is true of erythropoietin: a. increased erythropoietin results in a detectable increase of hemoglobin within 24 hours b. erythropoietin is primarily produced by the liver in adults c. erythropoietin levels are increased in the setting of renal failure d. erythropoietin gene expression is controlled by HIF-1 (hypoxia inducible factor) e. administration of recombinant erythropoietin can completely compensate for anemia due to iron deficiency 1 out of 1 The correct answer is d. Erythropoietin gene expression is controlled by HIF-1 (hypoxia inducible factor) a) erythropoietin stimulates red blood cell precursors in the marrow to produce more RBC but the effects of this take several days to manifest in the peripheral blood b) erythropoietin is produced by kidneys in response to hypoxia c) opposite is true d) true e) without sufficient iron to make RBC, erythropoietin stimulation of RBC precursors cannot correct anemia Question 5 of 15 Which of the following is virtually DIAGNOSTIC of iron deficiency anemia: a. low serum iron (less than 50 ug/dL)
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Quiz 01 - Ans - Quiz 1 Answers d. Arise from a common...

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