Lecture 4 (Structure and Function of Normal Cells)

Lecture 4 (Structure and Function of Normal Cells) -...

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Foundations Lecture 4 9-8-10 (Week 1) Learning Objectives Recognize that cells are the basic units of life Identify the appearances and functions of the following major organelles: In general… - Membrane-enclosed organelles allow for specialization perform different functions - Compartmentalization allows for division of labor Nucleus - Primary Functions o (1) DNA replication o (2) RNA transcription and processing o (3) Assembly of ribosomal subunits Nuclear Envelope - Regulation of cytonuclear exchange exchange through pores - Directions o Ribosomal subunits produced in the nucleus move out of the nucleus 1
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Foundations Lecture 4 9-8-10 (Week 1) o Proteins required by the nucleus are moved into the nucleus Ribosomes - Protein synthesis - Types o Free-floating o Attached to endoplasmic reticulum (rough ER) Synthesize 3 different types of proteins, which are then translocated into the endoplasmic reticulum… (see next heading) (1) Secretory Proteins (2) Lysosomal Enzymes (3) Membrane Proteins ER - ER functions to modify the proteins synthesized by the attached ribosomes form of “quality control” - ER then delivers to the golgi complex… Golgi complex - Transportation and posttranslational modification of the secretory proteins, then package for export Lysosomes - Intracellular digestion Mitochondria Structure - Abundant, and vary widely in shape 2
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This note was uploaded on 09/14/2011 for the course PHARM HB taught by Professor Staff during the Spring '11 term at UCSD.

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Lecture 4 (Structure and Function of Normal Cells) -...

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