Quiz Week 04

Quiz Week 04 - Question 1 of 18 1. Lynch syndrome a cancer...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Question 1 of 18 1. Lynch syndrome – a cancer syndrome resulting from a single gene disorder – can result from a mutation in the MSH2 gene, or the syndrome can result from a mutation in the PMS1 gene. Which of the following terms best describes this situation? A. Allelic heterogeneity. B. Locus heterogeneity. C. Reduced penetrance. D. Pleiotropy. E. Variable expressivity. 1 out of 1 The Correct Answer is B. Locus heterogeneity. Question 2 of 18 2. The inheritance pattern of a single-gene trait resulting from an ion channel defect is most likely to be which of the following? A. Autosomal dominant. B. Autosomal recessive. C. Mitochondrial. D. X-linked dominant. E. X-linked recessive. 1 out of 1 The Correct Answer is B. Autosomal recessive. Question 3 of 18 3. An unaffected woman has a child with a man affected by a fully penetrant X-linked dominant condition. Which of the following provides the correct probability of observing the affected phenotype in the described child? A. The probability that their first daughter will be affected = 1. B. The probability that their first child will be an affected daughter = 1. C. The probability that their first son will be affected = 1/2. D. The probability that their first child will be an affected boy = 1/4. E. The probability that their first child will be affected = 1/4. 1 out of 1 The Correct Answer is A. The probability that their first daughter will be affected = 1. Question 4 of 18
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4. Which of the following characteristics is least likely to describe the expression of the abnormal phenotype due to an autosomal dominant disorder? A. A person expressing an abnormal phenotype is more likely to be homozygous than heterozygous. B. An abnormal phenotype in a heterozygote may occur if a mutant protein interferes with function of normal protein (dominant negative effect). C. An abnormal phenotype may not be penetrant in a particular heterozygote. D. The phenotype of heterozygotes may be variable even within a single family. 0 out of 1 The Correct Answer is A. A person expressing an abnormal phenotype is more likely to be homozygous than heterozygous. Question 5 of 18 5. The Rh blood group gene on chromosome 1 has two alleles – RhD , which expresses RhD protein on red blood cells, and Rhd , which does not produce a protein on red blood cells. An Rh negative woman (no RhD protein on her RBCs) marries an Rh positive man (expresses RhD protein on his RBCs). The man’s
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 7

Quiz Week 04 - Question 1 of 18 1. Lynch syndrome a cancer...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online