Students GI TBL LOs and Drug List

Students GI TBL LOs and Drug List - Gastrointestinal Block...

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Unformatted text preview: Gastrointestinal Block TBL Drug List Antiemetic Drugs Ondansetron setron => 5-ht3 antag used as antimetic Prochlorperazine phenothiazepine d2 blocker also block h1, a1 and mucscarinc recetpros ie s/e of orthostatic hypotn and sedation Metoclopramide d2 blocker also bloc ks 5ht3 and agonists at 5ht4 prokinetic agents Dimenhydrinate muscarine/h1 blocker act centrally tx motion sickenss/vertigo need to cross into the BBB block h1 therefore sedation; anticholinergic s/e Meclizine see above Scopolamine see above Aprepitant nk1 blocker neurokinin block receptor subP,. Anteemetic Dronabinol agonists as antiemetic CB 1 agonists Dexamethasone agonists glucocorticoid agonists Drugs Used to Treat Acid-Related Disorders Antacids (containing magnesium, aluminum, or calcium)- generally contained these three things mg diahhraea, al contsitaption ,mg andal are combined to cancel out effect Cimetidine h2 blocker more special and ifferet block cyp and andgorn receptors (antiandrogen effects) Ranitidine h2 blocker s/e - none Omeprazole ppi h/k+ atpase on parieal cells most powerful way to knock out acid production Sucralfate al salt with disaccharide binds to ulcerated mucose - protect Misoprostol pg analog (pge1) used ofr nsid induced ucler Bismuth subsalicylate BSS moa: in the ugt actis loclally local protective effect + antimicrobial effect used for H. pylori eradication Metoclopramide used to acid asociated dixorder - used for GERd due to prokinetic to contract LES to prevent gastric acid from going back! Antimotility and Antisecretory Agents Loperamide opoid - stimualte opoid receptors in the gut stimulate intense segemetnal contraction inc transite time to pull more fluid Diphenoxylate + atropine sulfate - opoid...
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Students GI TBL LOs and Drug List - Gastrointestinal Block...

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