Students GI TBL LOs and Drug List

Students GI TBL LOs and Drug List - Gastrointestinal Block...

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Unformatted text preview: Gastrointestinal Block TBL Drug List Antiemetic Drugs Ondansetron – setron => 5-ht3 antag → used as antimetic Prochlorperazine – phenothiazepine – d2 blocker – also block h1, a1 and mucscarinc recetpros ie s/e of orthostatic hypotn and sedation Metoclopramide – d2 blocker also bloc ks 5ht3 and agonists at 5ht4 – prokinetic agents Dimenhydrinate – muscarine/h1 blocker – act centrally – tx motion sickenss/vertigo – need to cross into the BBB → block h1 therefore sedation; anticholinergic s/e Meclizine – see above Scopolamine – see above Aprepitant – nk1 blocker → neurokinin – block receptor subP,. Anteemetic Dronabinol – agonists as antiemetic – CB 1 agonists Dexamethasone – agonists – glucocorticoid agonists Drugs Used to Treat Acid-Related Disorders Antacids (containing magnesium, aluminum, or calcium)- generally contained these three things – mg → diahhraea, al → contsitaption ,mg andal are combined to cancel out effect Cimetidine – h2 blocker → more special and ifferet – block cyp and andgorn receptors (antiandrogen effects) Ranitidine – h2 blocker – s/e - none Omeprazole – ppi – h/k+ atpase on parieal cells – most powerful way to knock out acid production Sucralfate – al salt with disaccharide – binds to ulcerated mucose - protect Misoprostol – pg analog (pge1) → used ofr nsid induced ucler Bismuth subsalicylate – BSS → moa: in the ugt actis loclally – local protective effect + antimicrobial effect– used for H. pylori eradication Metoclopramide – used to acid asociated dixorder - used for GERd due to prokinetic → to contract LES to prevent gastric acid from going back! Antimotility and Antisecretory Agents Loperamide – opoid - stimualte opoid receptors in the gut – stimulate intense segemetnal contraction – inc transite time – to pull more fluid Diphenoxylate + atropine sulfate - opoid...
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This note was uploaded on 09/14/2011 for the course PHARM TBL taught by Professor Staff during the Spring '11 term at UCSD.

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Students GI TBL LOs and Drug List - Gastrointestinal Block...

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