Chap 7 Outline - Chapter 7 - Membrane Structure and...

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Chapter 7 - Membrane Structure and Function Objectives 1. Explain why phospholipids are amphipathic molecules. 2. Note the differences between the “sandwich” model and the fluid-mosaic model. 3. Explain what freeze-fracture techniques reveal about the arrangement of proteins in membranes. 4. Describe the fluidity of the components of a cell membrane. 5. Explain how membrane fluidity is influenced by temperature and membrane composition. 6. Distinguish between peripheral and integral membrane proteins. 7. List the major functions of membrane proteins. 8. Explain cell-cell recognition. 9. Explain how hydrophobic molecules cross cell membranes. 10. Distinguish between channel proteins and carrier proteins. 11. Explain how aquaporins facilitate the passage of water through 12. Define diffusion. Explain why it is a spontaneous process. 13. Distinguish among hypertonic, hypotonic, and isotonic solutions. 14. Define osmosis 15. Predict the direction of water movement based on differences in solute concentrations. 16. Describe how living cells with and without cell walls regulate water balance. 17. Distinguish among osmosis, facilitated diffusion, and active transport. 18. Describe the process of cotransport. 19. Explain how large molecules are transported across a cell membrane. 20. Distinguish between pinocytosis, phagocytosis and receptor-mediated endocytosis Key Term active transport adenosine triphosphate (ATP) amphipathic aquaporin carbohydrate concentration gradient diffusion endocytosis exocytosis electrochemical gradient facilitated diffusion flaccid gated channel glycogen glycolipid glycoprotein hypertonic hypotonic integral protein ion channel isotonic osmoregulation osmosis passive transport peripheral protein phagocytosis pinocytosis plasma membrane plasmolysis proton pump receptor-mediated endocytosis selective permeability sodium-potassium pump tonicity transport protein turgid Outline. A. Membrane Structure 1. Membrane models have evolved to fit new data. a. Davson & Danielli Model 1935-1970 - Proposed “sandwich” model b. Fluid mosaic model currently accepted - Proposed by Singer and Nicolson (1972), used freeze fractionation to separate the membrane layers. Fluid – phospholipids and proteins move laterally. The membrane is held together mainly by hydrophilic and hydrophobic attractions. Some proteins do not move as far or as fast as they are held in place by the cytoskeleton. Molecules rarely flip flop. (Fluidity = salad oil consistency to
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This note was uploaded on 09/14/2011 for the course BIOL 2301 taught by Professor Staff during the Spring '11 term at Lone Star College System.

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Chap 7 Outline - Chapter 7 - Membrane Structure and...

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