Renal Systems

Renal Systems - PT Thin DL Thin AL Thick AL DT CT...

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Substance Filtration Secretion Reabsorption Excretion Note Glucose Yes (100%) No Na+ Yes No Yes Yes Creatinine Yes Yes (15-20%) No Yes Neglect secretion C(cr)= GFR Overestimates GFR Inulin Yes No No Yes Clearance = GFR PAH Yes Yes Yes C(PAH)= RPF Low concentration no PAH in vein High concentration = saturable since actively secreted higher concentration in PT than inulin Albumin No No Yes No Urate Yes Yes Yes No
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For filtration Hydraulic pressure > oncotic pressure For capillary reuptake hydraulic pressure (interstitial ) < oncotic pressure (peritubular capillary)
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Unformatted text preview: PT Thin DL Thin AL Thick AL DT CT Reabsorptio n 2/3 Water 2/3 Na+ 2/3 K+ 2/3 Ca++ HCO3-70-80% phosphate 100% Glucose 100% AA 100% protein *the last three – as long as under the Tm limit Water Na+ Na+ Cl-Net K+ 15-20% Ca++ Mg++ 10-20% HCO3-80% NH4+ Na+ Ca++ 5-7% HCO3-Phosphate ADH : Water Na+ (Aldo) 5-7% HCO3- (CCD) Urea Secretion H+ NH4+ Urea K+ recycle H+ Net K+ NH3 NH4+...
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Renal Systems - PT Thin DL Thin AL Thick AL DT CT...

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