Study Design - Advantages & Disadvantages

Study Design - Advantages & Disadvantages - SPPS...

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Spring Quarter 2009 Jessica M. Bryan, MPH and Grace M. Kuo, PharmD, MPH 1 SPPS 208 Study Design Advantages and Disadvantages Study Design Advantages Disadvantages Experimental Study Investigator Intervention Comparison Groups selected Able to blind and control for variables Allow for evaluation of a single variable in a carefully defined population Measurement Instrument designed Used to evaluate the efficacy of drugs Demonstrates cause and effect relationships Costly and time-consuming Difficult to conduct Bias Too small population and too short of time period May be restrictive and measure surrogate end points Generalizability questionable Case-Control Study Well Suited for Rare Outcomes Well-suited to the study of events occurring after Long Periods of Time. Efficient in amount of Time needed to conduct a study and the Cost of a study Small Sample Size Yields Odds Ratio Retrospective and Observational- Not Experimental
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Study Design - Advantages & Disadvantages - SPPS...

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