{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}


11Pathogenimmuno_correl - Patterns of susceptibility to...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Patterns of susceptibility to infection with immune deficiencies (Numbers in parentheses refer to cases in Cases text; information adapted from Cases text) April Apperson, UCSD SOM OESS Opportunistic infections occur with an absence of functional T-cells = SCID (because need CD4+ T-cells for TD B-cell responses); opportunistic infections result from bacteria, viruses and fungi that normally reside non-pathogenically in our bodies because of ongoing control by cellular immunity, but become pathogenic without that immunity. Typical order of opportunistic infections that appear in an infant or adult: 1) thrush (severe yeast infection) in mouth and diaper area; 2) Pneumocystis carinii (fungus) infection in lungs causing cough; 3) intractable diarrhea due to overgrowth of enteropathic bacilli; 4) adults may also develop Aspergillus (fungus) infection in lungs causing cough Medical emergency because infants (or adult if SCID is acquired) die rapidly from infections even when treated adequately with antibiotics or antivirals.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}