Cases(SB) - Microbiology Cases Organism Features Host...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Microbiology Cases Organism Features Host Response Clinical Presentation Diagnosis Treatment Streptococcus pneumoniae (pneumonia) #1 cause community- acquired pneumonia gram +, catalase -, bullet shaped diplococcus capsule = most important virulence factor spread via resp droplets secretory IgA pneumonia (sudden-onset, fever, productive cough, +/- blood in sputum) common cause of sinusitis complications = gram stain culture: small/medium mucoid colonies w/alpha hemoloysis, optochin succeptible, bile succeptible antigen test penicillin if pen-resistant ceftriaxone or clindamycin 7-valent vaccine for children! Neisseria Meningiditis (meningitis) one of the usual suspects for meningitis (S. pneumo, N. meningiditus, H. flu….GBS in neonates) capnophillic, gram – cocci in pairs (coffee- bean shaped) has LOS instead of LPS meningitis belt in sub- Saharan Africa complement and Ig’s meningococcemia can start with flu-like sx, then petichial rash then pustules, bullae… sepsis DIC in a matter of hours +/- meningitis (HA, neck stiff, altered mental state, vomiting) gram stain culture (prefers chocolate agar) penicillin G or ceftriaxone ASAP tetravalent vaccine (polysaccaride capsular protein conjugate) for serotypes: A, C, Y, W135 * no coverage for serotype B
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Salmonella typhi (Typhoid fever) motile gram – rods strictly human dz, spread thru contaminated food/water typhi enters thru GI and disseminates thru blood. Non-typhoid salmonellas (typhimurium and enteritidis) stay in GI and cause enterogastritis) risk if immunocomp or sickle cell dz typhi: survives in Φ ’s by messing with phagolysosome fusion distrib to organs and get organ-specific dz. non-typhi: stays in GI, get GI dz, granulocyte response Typhoid fever present with fever of unknown origin (“PUO”). Fever, HA, ab discomfort, const or diarrhea… +/- bradycardia, “rose spots,” and hepatosplenomegaly +/- anemia and leukopenia complications: cholecystitis, endocarditis, osteomyelitis ~5% of ppl carriers (typhoid Mary) Non-typhoid salmonella self-limited diarrhea 12-48 hr incubation isolate and ID the organism Typhoid fever ampicilling, cipfofloxacin, or chloramphenicol vaccine-preventable (says in case but I’ve never heard of it) non-typhoid salmonella E. coli (UTI) UTI most often caused by E. coli. Other suspects are proteus, staph. Saprophyticus (young sexing woman), and pseudomonas (hospital) E. coli is gram – rod with peritrichous flagella and LPS UTI caused by normal bowel flora & more in women bc short urethra E. coli adheres to epithelial cells & prods toxin protected from host immune by K1 capsular antigen IgA and IgG prod cystitis (normal UTI): frequency of urination, dysuria (painful pee), and abdominal tenderness
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 9

Cases(SB) - Microbiology Cases Organism Features Host...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online