microNotes1 - Virus Bacteria Fungus Parasite Differences...

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DifferencesEukaryoteProkaryoteDrugsNuclearMembraneYesNoOrganellesBoundUnboundDigestivevacuolesYesNoChromosomesMultipleSingleDNA gyrasecan betargeted withquinoloneslikeciprofloxacinMembranesterolsYesNoPeptidoglycanNoYesPenicillins,cephalosporinsRibosomes80s70sAminoglycosides,MacrolidesMicrobiology BasicsPrionVirusBacteriaFungusParasiteNoNoYesYesYesNucleic AcidNoRNA/DNARNA and DNARNA and DNARNA and DNANucleusNoneNoneProkaryoticEukaryoticEukaryoticRibosomesNoneNone70s80s80sMitochondriaNoneNoneNoneYesYesOuterSurfaceNoneProteincapsidEnvelopeRigid wallPeptidoglycanRigid wallChitinFlexiblemembraneReplicationAggregatesRequireshostBinary fissionBudding ormitosisMitosisFunctions of normal flora•Prevent colonizationand infection withpathogens•Produce B vitamins andVitamin K in theintestine•Deconjugatebile acidsTyphoid Mary:first person identified as a healthycarrier ofSalmonella typhiin the United States.She infected 75 people over the course of 7 yearsSiteNormal FloraProblem ColonizersSkinS.epidermidisDiptheroidsProprionobacteriumacnesCandidaS.AureusPseudomonas aeruginosaNoseS. epidermisDiptheroidsStreptococciS. AureusMRSAClostridium perfinginsHumans normally have permanent, nonpathogenic residentbacteria and yeast on skin and mucosa. Their numbers are about10 times the number of human cells. The blood, lower respiratorytract, CSF, pleural fluid, peritoneal fluid, and urine are sterile anddo not contain any normal flora.Nile Law: California state law thatrequires the screening of all high-riskpatients for MRSA. High-risk criteriainclude: inpatient surgery, burn, ICU,dialysis, hospitalized or nursing homeShe infected 75 people over the course of 7 yearsas a cook and was quarantined for 26 years.MouthS.viridansBacteroidesFusobacteriumStreptococcus mutansPorphyromonasgingivalisThroatS.viridansNeisseriaspp.Haemophilusspp.S. pyogenies(Group A)MeningococciColonBacteroidesfragilisEnterobacteriaecaeLactobacillusEnterococciClostridiumC.difficileVancomycin-resistantenterococciVaginaLactobacillusStreptococciB. FragilisEnterobacteriacaeCandidaGroupB StreptococciClostridium perfinginsfrom the normal bowelflora can causemyonecrosisifinoculated into ananaerobic environmentin a wound.AttachmentColonizationInvasionEvasion ofhost defensesHost damageand InfectionSteps in Microbial PathogenesisSelecting antibiotics:choose an antibiotic towhich the pathogen islikely sensitive, butwhich has the mostlimited spectrum so asto limit thedevelopment ofresistance.
General Bacteria FeaturGram Stain:Gram positive cells have a thick layer ofpeptidoglycan, which serves as a barrierto lipid decolorizing solvents. Since thecells cannot be decolorized, they remainpurple despite addition of decolorizingagent.

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Term
Spring
Professor
staff
Tags
Bacteria, Escherichia coli, gram negative bacteria, GI Tract, Gram positive bacteria

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