Quiz 03 Soln

Quiz 03 Soln - Question Feedback 1 of 20 Which of the...

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Question Feedback 1 of 20 Which of the following statements is true about infection with Aspergillus fumigatus? A. A. fumigatus will not grow at body temperature so is more frequently a colonizer B. Infection is caused by the inhalation of infectious arthrospores C. Breaks in the skin are a common portal of entry D. Neutropenia is a major risk factor as neutrophils kill the invasive hyphal form E. Most infected patients develop disease 1 out of 1 The correct answer is D. A. fumigatus is the most common species of Aspergillus that infects humans, and because of that, it DOES grow at 37oC. Inhalation of conidia causes the infection, as the lungs are the site of initial infection.Arthrospores are the infectious form of Coccidioides. Rarely do patients who inhale conidia develop invasive aspergillosis, it is usually patients with an immune compromising state. 2 of 20 A 50-year old man presents with confusion and CT scan shows a focal lesion in his right tempero-frontal area. PCR of his cerebrospinal fluid is positive for Herpes simplex virus. Which of the following is true of the cause of his infection? A. This syndrome could be caused by either HSV 1 or HSV2 B. His infection is potentially fatal unless treated with an effective antiviral drug such as acyclovir C. It is caused by a RNA virus so is sensitive to reverse transcriptase inhibitors D. Normal appearing brain tissue next to the lesion will also be microscopically normal E. Red cells in the CSF rule out HSV infection. 1 out of 1 The correct answer is B. HSV encephalitis is a life-threatening infection and must be treated with acyclovir. The usual presenting symptoms are a rapid change in personality, and fever. It is caused by HSV-1 (a DNA virus) reactivation, and has a predilection for the tempero-frontal areas of the brain, where biopsy demonstrates necrosis and extensive viral involvement. Because of the necrosis, usually there are erythrocytes in the CSF. 3 of 20 A 28-year old woman who is 4 months pregnant presents with fever, cough and myalgias in January. A rapid test of a nasopharyngeal swab is positive for influenza. Which of the following is true of the cause of her infection? A. The presence of fever, headaches, and myalgia are due to the widespread dissemination of the virus B. Only the very young and elderly are at risk of dying from this infection. C. Every infected patient should be treated with antivirals to decrease the risk of spread to others D. Emergence of a new pandemic strain may arise from reassortment of human and avian viruses in another animal host E. Live attenuated vaccine is indicated for immunocompromised patients because of their limited immune response 1 out of 1 The correct answer is D. Influenza is a DNA virus that was originally a disease of waterfowl, yet through agriculture has affected swine and humans. All patients with influenza have symptoms of fever, headaches, and myalgias, which are due to cytokine release and not viremia. Influenza is extremely infectious, and those less than 2 or
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This note was uploaded on 09/14/2011 for the course PHARM mb taught by Professor Staff during the Spring '11 term at UCSD.

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Quiz 03 Soln - Question Feedback 1 of 20 Which of the...

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