Lecture 18 - Tissue and Cellular Organization of Muscle...

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Tissue and Cellular Organization of Muscle
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Muscle: Structure and Function Three types of muscle: 1. Skeletal Muscle 2. Cardiac Muscle 3. Smooth Muscle Basic function of all three types is the same: Generate Tension
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Structural Organization of Skeletal Muscle Groups of muscles Deep Fascia Muscle Epimysium Fascicle Perimysium Muscle fiber Endomysium
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Structural Organization of Skeletal Muscle Organ Tissue Cell Subcellular
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Cellular and Subcellular Skeletal Muscle Structure 1. Muscle cells are called ‘fibers’ can be very large (100 μ m in diameter, many cm long) 2. Typically ‘multinucleate’ arising from fusion of ‘myoblasts’
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• After birth, growth of muscle fibers happens by hypertrophy rather than hyperplasia – muscle fibers cannot undergo mitosis. • Satellite cells have the ability to undergo mitosis after birth to aid in muscle regeneration.
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3 Units of Organization 1) Conduction of electrical signals sarcolemma 2) Control of muscle contraction sarcoplasmic reticulum 3) Contraction myofibrils
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