pol table-filled

pol table-filled - DnaG primary responsibilities(secondary...

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DnaG DNA Pol I DNA Pol III DNA Pol δ / ε DNA Pol α Primase Telomerase DNA Pol V primary responsibilities (secondary responsibilities) nuclease activity? INITIAL nuclease substrate 3’OH needed in polymerization? ds/ss DNA junction in polymerization? Template/Primer used sequence specifc? how is it recruited to its substrate? processive? none/ low or high? accurate? Make RNA primer Primer removal (DNA repair - BER, NER) genome replication (DNA repair - mismatch, HR) genome replication (some DNA repair) Make DNA primer Make RNA primer Extend linear chromosome ends SOS response, polymerize over unfxable damages No 5’->3’ exonuclease, 3’->5’ exonuclease 3’->5’ exonuclease 3’->5’ exonuclease No No - No. .. (?) - 5’->3’ exo: nicks ds region with an RNA primer 3’->5’ exo: ss/ds DNA junction with 3’OH resulted From a mispaired nucleotide (exposed 3’ end with a 5’ overhang From mispairing) Same as Pol I’s 3’->5’ exonuclease activity
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