notes4 - T = Thymine(a base not a nucleotide Note that a...

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Bio 20A-M. Dalbey Macromolecules 4/2/08 1 of 2 Assigned Reading: Chapter 3 3.3 What are the Chemical Structures and Functions of Carbohydrates? p. 49 3.5 What are the Chemical structures and Functions of Nucleic Acids? p. 57 3.5 NUCLEIC ACIDS Nucleic acids are linear polymers of nucleotides (i.e. they are polynucleotides). Know the difference between "nucleotide" "nucleoside" "base" BASE NUCLEOSIDE adenine (deoxy)adenosine thymine (deoxy)thymidine guanine (deoxy)guanosine cytosine (deoxy)cytidine uracil (deoxy)uridine ATP is a "nucleotide" or "nucleotide triphosphate" Abbreviations are frequently used to refer to nucleotides and bases. ATP = adenosine triphosphate dTMP = deoxythymidine monophosphate
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Unformatted text preview: T = Thymine (a base, not a nucleotide) Note that a polynucleotide has structural polarity (5' vs 3') analogous to the C - N structural polarity of a polypeptide. (See the labeling in Figs. 3.24 and 3.25.) Polynucleotides are always elongated by adding new nucleotides onto the 3' end. The 5' end is oldest. Moreover, the 5' end of a gene transcript codes for the N-terminal region of the protein product of that gene. N N N N N : H H δ + δ-O OH HO C O P O O P O O P O O-O-O-O-1' 2' 3' 4' 5' H H ATP ADENINE (Nitrogenous Base) ADENOSINE (Nucleoside) ADENOSINE TRIPHOSPHATE (Nucleotide) Ribose Phosphate X 3 Bio 20A-M. Dalbey Macromolecules 4/2/08 2 of 2 RNA DNA Ribose X Sugar 2’-Deoxyribose X Adenine X X Purine Guanine X X Thymine X Cytosine X X Nitrogenous Base Pyrimidine Uracil X TEXT/SELF-QUIZ p. 66. #1, 3, 4, 9....
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