AUTOIMMUNE DISORDERS

AUTOIMMUNE DISORDERS - Prepared by: Mark Dino B. Albiela,...

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Prepared by: Mark Dino B. Albiela, R.N.
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A Group of 60 to 80 chronic inflammatory diseases with genetic predisposition and environmental modulation Prevalence of 5% to 8% in US Prevalence is greater for females than males 75% of cases 4 th largest disease class in women
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Genetic (HLA type) Female X chromosome inactivation Environmental Smoking with RA Drugs Procainamide, minocycline, quinidine Infections
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Tissue/ Organ Specific Hashimoto’s Thyroiditis Myasthenia gravis Multiple sclerosis Not tissue specific, but tend to accumulate forming inflammatory response Renal glomerulus Hepatic Small bile ductules Systemic Systemic lupus erythematosus Rheumatoid arthritis
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The mechanism that causes immune system to  recognize host tissue as foreign is not clear. The  following factors are the possible contributors to  autoimmune disorders: Release of previously “hidden” antigens into the 
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AUTOIMMUNE DISORDERS - Prepared by: Mark Dino B. Albiela,...

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