Notes Feb 12 - Notes Feb 12 Lecture 8- Fig 25.5-6 o Okazaki...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Notes Feb 12 Lecture 8- Fig 25.5-6 o Okazaki fragments made on the lagging strand o Lagging strand is made backwards 5-3 relative to the replication fork o DNA polymerase cant start new chains o Strands start with RNA by RNA polymerase called primase Uses ribonucleoside triphosphates Can start new chains at the 5 end without a primer Associated with proteins at the replication fork to keep the DNA replicated at a rapid speed- replisome complex Travels along the template of the lagging strand Lays down RNA nucleotides complementary to the template Does not require a specific sequence, instead it lays down primers at random every once in awhile and then stops very quickly RNA piece is very small because primase just stops Makes half-a-turns worth of RNA (10 bases would be a full turn) o Know the direction of which RNA primer is placed first by primase Fig 8.11/5-13- The old primer is replaced by DNA- There are different enxymes that can chew up the RNA polymerase- If there is some nuclease the chews up the RNA, then it leaves a gap- The DNA polymerase I can replace RNA and place DNA by elongationg...
View Full Document

Page1 / 3

Notes Feb 12 - Notes Feb 12 Lecture 8- Fig 25.5-6 o Okazaki...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online