outline 9 - Biological Sciences 110a Fall 2011 Lecture...

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Biological Sciences 110a, Fall 2011 Lecture Outline #9: Membrane transport reading: Section 4.7 The erythrocyte membrane integral membrane proteins allow ions to cross peripheral membrane proteins anchor the membrane to the cytoskeleton Membrane transport passive transport (does not require energy input) simple diffusion (oxygen, water, small hydrophobic molecules) facilitated diffusion example: the glucose transporter (specific glucose binding site) example: ion channels (aqueous channel, selective ion binding site) regulated (among other ways) by gating - voltage-gated and ligand-gated ion channels active transport (requires energy input) specific binding sites for transported ions or molecules structural change during transport (facilitated diffusion may also involve specific binding sites and structural changes, but active transport must involve them) energy from a variety of sources Na + /K + ATPase (example of energy from a chemical, ATP) Na + /glucose symport (example of energy from a concentration gradient) cotransport
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