question9 - Overall Diagram: Part A Diagram: Part B...

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Overall Diagram: Part A Diagram:
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Part B Mechanism: Neo40 is a proprietary blend including beetroot and Hawthorne berry. The beetroot apparently provides nitrates, while the Hawthorne berry provides an effective nitrite reductase.[9.b.1] The body naturally converts nitrates to nitrites by absorbing them in the small intestine, then concentrating them in the saliva, where facultative anaerobic bacteria reduce them to nitrites (using the nitrate as a final electron acceptor).[9.b.1] The apparent effect of Neo40 results from it increasing the amount of NO available to the soluble Guanyl Cyclase (sGC, or type II Guanyl Cyclase, BRENDA 4.6.1.2, PDB 2WZ1). TODO: put picture here Part C Mediterranean Diet: Endothelial nitric oxide synthase (eNOS) activity in cultured cells is increase in response to addition of thyme and wild artichoke extracts added in vitro . The presence of these extracts also increases the expression of eicosanoid prostacyclin.[9.c.1] Prostacyclin is a prostoglandin which acts by exerting its influence against PGI receptor, a G-
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question9 - Overall Diagram: Part A Diagram: Part B...

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