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phospholipidbiosyn - Enzymes Proteins Other Players in...

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Hormone sensitive lipase in fat cells, hydrolyzes TG to release fatty  acids, controlled by glucagon, epinephrine  & insulin Albumin carries fatty acids in blood stream Glycerol kinase produces glycerol-3-phosphate  Glycerol-3-phosphate dehydrogenase oxidizes G3PD to DHAP for glycolysis Fatty acyl-CoA synthetase (thiokinase) uses ATP & CoA to activate fatty acids carnitine small molecule used to transport fatty  acids into mitochondrion Carnitine acyl transferase I &II adds fatty acyl to carnitine from fatty acyl  CoA & removes  Acyl-CoA dehydrogenase, hydratase, OH acyl-CoA dehydrogenase dehydrogenates (oxidizes) fatty acyl CoA,  hydrates and oxidizes to ketone at beta  position Acyl-CoA acetyltransferase removes acetyl-CoA by attack of CoA  leaving shortened acyl CoA Propionyl-CoA carboxylase adds CO 2  to propionyl-CoA to form  methylmalonyl –CoA, uses ATP, biotin &  B12 Enzymes, Proteins & Other Players in Enzymes, Proteins & Other Players in Triacylglyceride & Fatty Acid Degradation Triacylglyceride & Fatty Acid Degradation
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Ketone bodies acetoacetone, D-beta hydroxybutyrate and  acetone Thiolase puts 2 acetyl CoAs together to form  acetoacetyl-CoA HMG-CoA synthase adds a 3 rd
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