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BIO203_Cardiovasc_1 - The cardiovascular(circulatory system...

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1 The cardiovascular (circulatory) system and its physiology are significant in several regards: Evolution : multicellularity and tissue specialization, coupled with increased size, require bulk transport of important materials Organism : distribution of respiratory gases, nutrients, chemical messengers, etc ., in a dynamic and adaptive manner to meet physiological needs Health and Disease : breakdown of homeostatic mechanisms can jeopardize life; adaptive responses to challenges can promote survival; clinical applications ( ex ., angiogenesis) M. Feder, Adv. Physiol. Educ. 29: 3-10, 2005 Bulk Transport Systems Components Propulsive organs (hearts; chambered, tubular, ampullar, pulsating vessels) Pressure reservoir and distributors (arteries) Transfer systems (capillaries) Blood reservoir and return system (veins) Types – Open – Closed Open vs . Closed Circulatory Systems OPEN CLOSED hemolymph [fluid] blood vessels/hemocoel [compartment] vessels 30% of body volume [compartment volume] 5-10% of body volume 5-10 mm Hg [pressure] 75-150 mm Hg
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