BIO203_ImmuneDef

BIO203_ImmuneDef - J Travis Science 324 580-582 2009 J...

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J. Travis, Science 324: 580-582, 2009
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J. Travis, Science 324: 580-582, 2009
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Chemical and Immune Defense Systems External chemical defense systems toxins irritants [Barrier Function] Internal defense systems immunity o defense against pathogens (viruses, bacteria, parasites) o repair of tissue damage o immune surveillance against abnormal cells (cancerous tissue)
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Immune Defense Systems Innate immune system non-specific inherent rapid response widespread in animals Adaptive/acquired immune system specific targeting to foreign material/agent/cell induced response (adaptive) slower development of active response capability restricted to vertebrates, generally
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Key feature of immune defense systems: self vs . non-self recognition pattern recognition proteins (receptors) RECOGNIZE AND BIND WITH NON-SELF MACROMOLECULES
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The immune system comprises diffuse components: individual immune cells (leukocyte derivatives) secreted proteins complement antibodies
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BIO203_ImmuneDef - J Travis Science 324 580-582 2009 J...

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