BIO203_Neurophysiol_2

BIO203_Neurophysiol_2 - Neuron Nernst Equation RT [ion]out...

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1 Sherwood, Klandorf & Yancey, Animal Physiology: From Genes to Organisms , Figure 4-11 Neuron Nernst Equation E ion = log Walther Nernst 1864-1941 1920 Nobel Prize 58 mV [ion] out z [ion] in E ion = ln RT [ion] out zF [ion] in For ions at 20 ° C (and converting to log 10 ): Constant Field Equation (or, the Goldman-Hodgkin-Katz Equation) RT P K [K + ] o + P Na [Na + ] o + P Cl [Cl ] i FP K [K + ] i + P Na [Na + ] i + P Cl [Cl ] o E m = ln Electrical Equivalent Circuit of the Cell Membrane EXTRACELLULAR SPACE CYTOPLASM R Na R K R Cl C m E Na E K E Cl + + +
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2 E m when g Cl predominates Membrane Potential E m when g Na predominates E Na 0 mV E Cl E K E m when g K predominates Chord Conductance Equation Expresses the transmembrane electrical potential difference as the weighted average (by relative conductance) of the equilibrium potentials of ions g K E K + g Na E Na + g Cl E Cl g total E m = Sherwood, Klandorf & Yancey, Animal Physiology: From Genes to Organisms , Figure 4-7a,b,c Sherwood, Klandorf & Yancey, Animal Physiology: From Genes to Organisms , Figure 4-7d,e
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3 Cable Properties Cable theory or core conductor theory
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This note was uploaded on 09/16/2011 for the course BIO 203 taught by Professor Loretz during the Fall '09 term at SUNY Buffalo.

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BIO203_Neurophysiol_2 - Neuron Nernst Equation RT [ion]out...

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