BIO203_SensoryPhysiol_2

BIO203_SensoryPhysiol_2 - Mechanoreception Pacinian...

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1 Mechanoreception mechanosensitive channel channel opens receptor/generator potential AP initiation and/or change in neurotransmitter release physical perturbation Sherwood, Klandorf & Yancey, Animal Physiology: From Genes to Organisms , Figure 6-5 Pacinian Corpuscle: A Skin Touch/Pressure Receptor M.R. Miller et al ., Am. J. Anat. 102:183-217, 1958 M.R. Miller et al ., Am. J. Anat. 102:183-217, 1958
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2 J. Scheibert et al ., Science 323: 1503-1506, 2009 J. Scheibert et al ., Science 323: 1503-1506, 2009; Figure 1 J. Scheibert et al ., Science 323: 1503-1506, 2009; Figure 2 smooth biomimetic fingertip textured biomimetic fingertip Hair Cell Hair cells possess processes (kinocilium and stereocilia) that transmit small mechanical stimuli (displacements, vibrations, etc .) to mechanosensitive channels that, in turn, transduce a mechanical disturbance into a coded electrical signal. Eckert Animal Physiology , Figure 7-24a,b;