Lecture 6-2nots

Lecture 6-2nots - Kidney 10/6 Kidney: summary What weve...

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Unformatted text preview: Kidney 10/6 Kidney: summary What weve lear ned so far Urine formation by filtration Functional unit = nephron Bowmans capsule: where filtration occurs Proximal tubule Absorbs ~2/3 of NaCl, water Absorbs glucose Secretes organic cations and anions Proximal tubule Fluid exiting proximal tubule has 1/3 the volume Same , C NaCl 3x higher conc of inert solutes <3x higher conc glucose >3x higher conc bile salt, epinephrine Sherwood Klandorf Yancey Fig. 12-8 (detail) Nephron What weve lear ned so far Bowmans capsule: where filtration occurs Proximal tubule Loop of Henle Descends further into the medulla in organisms that make hyperosmotic urine (juxtamedullary nephrons) Juxtamedullary nephron Mammals which make more concentrated urine (desert mammals) Have higher medullary volume Have higher serosa in medulla Sherwood Klandorf Yancey Fig. 12-29 Nephron What weve lear ned so far Bowmans capsule: where filtration occurs Proximal tubule Loop of Henle Descending limb: thin, no brush border Passive loss of water, NaCl Loses water because serosa is high Hyperosmotic urine! Loop of Henle Descending limb P Na , P Cl low =>no absorption or secretion P high=>filtrate comes to osmotic equilibrium with serosa . = 300 Sherwood Klandorf Yancey Fig. 12-27 (detail) Nephron Bowmans capsule: where filtration occurs Proximal tubule Loop of Henle Descending limb: thin, no brush border Ascending limb: Thin, no brush border Loop of Henle Ascending limb, lower Thin: no brush border Rises to region of lower external...
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This note was uploaded on 09/16/2011 for the course BIO 203 taught by Professor Loretz during the Fall '09 term at SUNY Buffalo.

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Lecture 6-2nots - Kidney 10/6 Kidney: summary What weve...

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