8-26-08 - Advanced Biochemistry and Chemical Biology...

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Advanced Biochemistry and Chemical Biology CHM4034 Spring 2008 Dr. Lyons office hours lyons@chem.ufl.edu 846-3392 - W 10-11 AM - T,R 4:00-5:00 PM Class website http://www.chem.ufl.edu/~lyons/
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Greek lettering scheme used to identify the atoms in amino acid side chains 2 3 4 5 6 7 1
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An α -amino acid
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Glycine α +H 3 N C O - H S H α Alanine +H 3 N C O O - CH 3 H α Non-polar, aliphatic Valine +H 3 N C O - CH H H 3 C CH 3 α β γ 2 γ 1 β
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Non-polar, aliphatic β γ δ 2 δ 1 Leucine +H 3 N C C O O - CH 2 H CH H 3 C CH 3 α Isoleucine β δ γ 2 γ 1 +H 3 N C C O - H H 3 C H CH 2 CH 3 α
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Non-polar, aliphatic β γ δ ε Methionine +H 3 N C O - CH 2 H CH 2 S CH 3 α Proline β γ δ N H C O O - CH 2 CH 2 H 2 C α 2 +
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Phenylalanine β γ δ 1 δ 2 ε 1 ε 2 ζ 1 +H 3 N C O O - CH 2 H α Aromatic Tyrosine β γ δ 1 δ 2 ε 1 ε 2 ζ 1 η +H 3 N C O - CH 2 H OH α
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+H 3 N C O O - CH 2 H H N β γ δ 1 δ 2 ε 1 ε 2 ε 3 ζ 2 ζ 3 η Tryptophan α Aromatic
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γ Serine β +H 3 N C O - CH 2 H OH α Polar, uncharged β Cysteine γ +H 3 N C O O - CH 2 H SH α β γ 2 γ 1 +H 3 N C O - H H OH CH 3 α Threonine
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γ Asparagine β δ 1 δ 2 +H 3 N C O - CH 2 H C O NH 2 α Polar, uncharged +H 3 N C O - CH 2 H C O NH 2 H 2 C β Glutamine γ δ ε 1 ε 2 α β γ Histidine δ 1 δ 2 ε 2 ε 1 +H 3 N C O - CH 2 H NH + HN α
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η 1 β γ δ ε ζ η 2 Arginine +H 3 N C O - CH 2 H CH 2 CH 2 NH C NH 2 + H 2 N α Positively Charged +H 3 N C C O - CH 2 H CH 2 CH 2 CH 2 NH 3 + β γ δ ε ζ Lysine α
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δ ε 1 Glutamate β γ ε 2 +H 3 N C O - CH 2 H C O O - H 2 C α Negatively Charged β γ Aspartate δ 1 δ 2 +H 3 N C C O - CH 2 H C O O - α
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Alanine Ala A Cysteine Cys C Glycine Gly G Histidine His H Isoleucine Ile I LeucineLeu L
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This note was uploaded on 09/20/2011 for the course CHM 4034 taught by Professor Staff during the Summer '11 term at University of Florida.

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8-26-08 - Advanced Biochemistry and Chemical Biology...

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