Organic 2 Review Problem 392

Organic 2 Review Problem 392 - 376 PRACTICAL O RGANIC...

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376 PRACTICAL ORGANIC CHEMISTRY GENERAL REACTIONS. 1. Do not give the isocyanide reaction. 2. Give acetyl derivatives. 3. Give benzoyl and toluene- p -sulphonyl derivatives. 4. With nitrous acid give nitrosamines. 5. Give coloured oxidation products. 2. Acetylation. Proceed as in 2 (p. 373). Pour the final acetylation mixture into 10 ml. of water, and add 10% NaOH solution, with stirring, until no more anilide is precipitated (acetyl-monoethylaniline is very soluble even in dil. acetic acid: acetyl-diphenylamine readily separates without the addition of alkali). Filter, wash with water and recrystallise. Note. The acetyl derivatives in Class (ii) are usually water-soluble and some are liquid. (M.ps., p. 552.) 3. Benzoyl and Toluene-p-sulphonyl derivatives. Proceed as in '3 (p- 374)- The benzene-sulphonyl derivatives can be similarly prepared. Note. The sulphonyl derivatives of secondary amines are neutral and insoluble in alkali, and separate on formation. (M.ps., p. 552.) 4. Formation of nitrosamine,
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This note was uploaded on 09/19/2011 for the course CHM 2211 taught by Professor Castalleano during the Fall '06 term at University of Florida.

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