lec1 note - LECTURE 1 23 August 2010(Peter J Hollenbeck...

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-1- LECTURE 1. 23 August 2010 (Peter J. Hollenbeck) BIOL 231 Overview of Biology 231 Read: Chap. 1; DVD 1.5 through-1.11; 15.6 Problems: 1 & 2 In this course, we want to help you strengthen your abilities to: 1. Understand the process of scientific discovery. By this we mean to interpret experimental data, and to recognize how a well-designed experiment leads to new knowledge. 2. Pull together and evaluate new ideas – also known as thinking for yourself. In an age of startling gullibility, this is important outside of biology class too! I. Three overarching themes that will run through this course: A. The structure of molecules, organelles and cells underlie the way that they work. You have heard before that “structure determines function.” In cell biology, when we talk about “structure,” we mean the shape and organization of molecules, organelles and cells. We will also use the term "topology" when we talk about how the constituent parts of a cell are related or arranged in 3 dimensions. The structures of molecules, organelles and cells determine their functional properties, examples: 1. An actin filament vs a myosin molecule (which is a track, which is a motor?) 2. A lysosome (spherical, things happens throughout its volume) vs the endoplasmic reticulum (extended, important things happen mainly at its surface) How are cells organized in 3 dimensions? Consider two cell shapes & functions: 1.
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