3) Early Drosophila I

3) Early Drosophila I - 8/30/10 Bring the last few lecture...

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8/30/10 1 Bring the last few lecture slides that we didn’t get to in Thursday’s lecture Developmental Biology BIOL 3090-001 Lecture 3) Development of the Drosophila Body Plan I
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8/30/10 2 Lecture Outline Drosophila model Large scale screening for developmental mutants Maternal factors set up the body axes AP axis formation – Bicoid morphogen DV axis formation How is polarity initiated? Patterning of the Drosophila Embryo • AP and DV axes laid out in egg • Axes divided in the embryo – Parasegments • Segments distinguished by denticles and bristles on the cuticle
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8/30/10 3 Screening For Developmental Mutants • Screen • EMS mutagen • Balancer chromosome • DTS • Saturating screen Maternal Effect Mutations The genotype of the mother is expressed in the phenotype of its offspring Paternal contribution has no effect m / m x +/+ m /+ Phenotype +/+ x m / m m /+ Phenotype m /+ x m /+ m / m Phenotype
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8/30/10 4 Setting Up the Body Plan: Sequential Gene Expression Maternal genes:
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This note was uploaded on 09/18/2011 for the course BIOL 3090 taught by Professor Steven during the Spring '10 term at Toledo.

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3) Early Drosophila I - 8/30/10 Bring the last few lecture...

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