4) Early Drosophila II

4) Early Drosophila II - Developmental Biology BIOL...

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9/1/10 1 Developmental Biology BIOL 3090-001 Lecture 4) Development of the Drosophila Body Plan II Lecture Outline Finish AP axis formation DV axis formation Initiation of polarity Localization of maternal factors Patterning the early embryo: zygotic genes – DV patterning: Dpp – Gap genes and how they are controlled – Pair-rule genes
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9/1/10 2 Oocyte-Follicle Cell Interactions A/P and D/V axes are established by interactions involving Gurken Activates the receptor Torpedo Signal specifies POSTERIOR follicle cells Follicle cells signal back causing rearrangement of cytoskeleton Gurken further induces DORSAL follicle cells mRNA Localization in the Egg bicoid mRNA transported to anterior on MTs towards “+” end oskar mRNA transported to posterior on MTs towards “-” end oskar mRNA and protein – nucleate the assembly of the pole plasm – localize nanos mRNA
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9/1/10 3 Dorsal Protein Controls the Expression of Zygotic
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This note was uploaded on 09/18/2011 for the course BIOL 3090 taught by Professor Steven during the Spring '10 term at Toledo.

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4) Early Drosophila II - Developmental Biology BIOL...

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