Dev Biol 11) C. elegans Development 9.30 - 2 spp

Dev Biol 11) C. elegans Development 9.30 - 2 spp - 9/29/10...

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9/29/10 1 Developmental Biology BIOL 3090-001 Lecture 10) C. elegans Development Lecture Outline Molecular signals involved in induction Segmentation of the hindbrain: Ephrins and Hox genes Neural Induction C. elegans Development C. elegans as a model system Formation of A/P and D/V axes: asymmetric cell divisions and cell-cell interactions RNAi Cell-cell signaling in early development - Notch/Delta - Wnt: MOM and POP
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9/29/10 2 C. elegans Life Cycle Small soil-dwelling nematode Exist mainly as hermaphrodites (reproduce by self fertilization) Additional C. elegans Characteristics Transparent Simple anatomy Early larval stages can be frozen and revived later The first multicellular animal to have its genome completely sequenced
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9/29/10 3 C. elegans Anatomy (L1) Four molting stages before adult Post-embryonic development essentially additions to the larval body plan C. elegans Cell Lineage The complete cell lineage including all 959 somatic cells was determined by John Sulston Organs not usually derived from one sub-lineage
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9/29/10 4 C. elegans Embryogenesis
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Dev Biol 11) C. elegans Development 9.30 - 2 spp - 9/29/10...

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