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Unformatted text preview: removed form the aqueous environment is worth ~3K/mol stabilization energy Disulfide linkages are important to extracellular proteins Quaternary Structure Most proteins contain multiple subunits often identical Hemoglobin 4 subunits Why compose a protein of multiple subunits? 1) Easier to synthesize a large protein from several identical pieces 2) Repair easier to repair one defective subunit than an entire protein 3) Large proteins are better suited to unusual conformations 4) Multiple active sites mechanisms to regulate enzymatic activity...
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This note was uploaded on 09/19/2011 for the course CHEM 43 taught by Professor Therien during the Fall '09 term at Duke.
- Fall '09