pedigree question

pedigree question - Pedigree Detailed Answer Discussion...

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Unformatted text preview: Pedigree Detailed Answer Discussion Section Handout #7, Question 6 6) Below is the pedigree for a particular non-lethal disease: a. Is the disease trait dominant or recessive? The disease trait is dominant. To confirm this, look at the first mating in the F2 generation. If the trait was recessive, these two parents with the disease would be unable to produce any progeny that did not have the disease. b. Is the disease trait autosomal or sex-linked? The trait is autosomal, since there does not appear to be a clear pattern of one sex having a greater incidence of the disease than another. c. Is the disease linked to the A locus? Which (if any) of the F2 or F3 generations are recombinant? In order to answer this question, it is probably easiest to start by examining the P-F2 generations. If you look at just P-F2, it appears that the disease usually co-segregates with the A1 allele. Note that we are not trying to determine whether A is the locus where the disease is carried; instead, we...
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pedigree question - Pedigree Detailed Answer Discussion...

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